3.1.2: Sickle Cell Diaries Activity 3.1.1: Blood Detectives
In the lab above, we can understand that because of sickle cell anemia, sickled cells are not able to flow properly, causing other cells to not flow properly as well. This can cause further problems in the individual, whether it be blood clots to a sickle cell crisis. (Reduced blood cell count, and an elevated white blood cell count as well as a reduced hematocrit.)
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Normal red blood cells flow through the blood and carry oxygen efficiently. Sickled cells on the other hand have damaged hemoglobin and can both carry less oxygen, and clog vessels easily due to their new shape. Sickled cells are crescent shaped and cause blood clots to occur more frequently. Above shows the difference in shape between a normal RBC versus a sickled RBC.
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3.3.1: How is DNA Passed Through Generations?
As we know, Sickle Cell Disease is hereditary. Here, we can see how someone can carry it through Genotypes and Phenotypes.
Sickle cell anemia is highly prominent within the African American population. Carriers of this trait, not sufferers of the disease, contain an immunity to malaria. Carrying sickle cell anemia is a recessive trait.
Sickle cell anemia is highly prominent within the African American population. Carriers of this trait, not sufferers of the disease, contain an immunity to malaria. Carrying sickle cell anemia is a recessive trait.